The investigators are studying the utility of intra-operative magnetic resonance imaging (iMRI) during transsphenoidal pituitary surgery for large macroadenomas by randomizing patients to either an intra-operative MRI after resection, or no intra-operative MRI. The investigators will then count the number of gross total resection in each group of patients and also the complications related to surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
SINGLE
Enrollment
10
Intra-operative magnetic resonance imaging under general anesthesia
Routine transsphenoidal resection of pituitary macro adenomas
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, United States
Rate of gross total or maximal resection
Determine whether use of iMRI in transsphenoidal pituitary surgery for pituitary macroadenomas significantly increases the rate of maximal resection
Time frame: 24 hours after surgery
Operative time
Length of operation
Time frame: intraoperative
Frequency of post-operative CSF leak
Frequency of post-operative Cerebrospinal Fluid (CSF) leak
Time frame: 30 days post surgery
Rate of Readmission
Frequency of readmission
Time frame: 30 days post surgery
Length of anesthesia time
Length of time participant is under anesthesia
Time frame: intraoperative
Rate of post-operative endocrinopathies
Rate of post-operative endocrinopathies
Time frame: 30 days post surgery
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