Autonomic Responses During the Valsalva Maneuver and Deep Breathing Test Depend on the Experimental Setup

Danish Pain Research Center40 enrolled

Overview

The purpose of this study is to determine the effects of procedural differences during the Valsalva maneuver and deep breathing test in autonomic nervous system testing.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Autonomic Nervous System Diseases

Interventions

Autonomic Function TestingOTHER

Autonomic nervous system index assessed with Task Force Monitor (CNSystems Medizintechnik AG, Graz, Austria)

Eligibility

Sex: MALEMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * male * ≥ 18 year * normal ECG-12 Exclusion Criteria: * any known disease * smoking * any intake of regular medicine

Locations (1)

Danish Pain Research Center, Aarhus University Hospital

Aarhus, Denmark

Outcomes

Primary Outcomes

Blood pressure changes to cardiovascular adrenergic activation

Time frame: 3 hours

Heart rate changes to parasympathetic activation

Time frame: 3 hours

Secondary Outcomes

Expiratory pressure during the Valsalva maneuver

Time frame: 3 hours

Expiratory duration during the Valsalva maneuver

Time frame: 3 hours

Air volume exchanged per respiratory cycle during deep respiration

Time frame: 3 hours

Data from ClinicalTrials.gov

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