Partially Hydrolyzed Whey Formula in Cow's Milk Allergic Patients

Inclusion Criteria: * age 0.5-18 years old * positive skin prick tests (SPT) or detectable serum milk specific IgE and a history of an allergic reaction to milk within 6 months before study screening; or milk-specific IgE level or SPT highly predictive for clinical reactivity (if ≤ 2 years old, sIgE \>2 kU/L; if \> 2 years old, a level \>5 kU/L; SPT wheal diameter ≥ 3 mm) * a clinical reaction during the cows milk oral food challenge Exclusion Criteria: * negative SPT and undetectable milk-specific sIgE * unstable asthma, allergic rhinitis, or atopic dermatitis * milk-induced eosinophilic gastroenteropathy * recent reaction to partially hydrolyzed whey formula * history of severe anaphylaxis with hypotension to cows milk * participation in any interventional study for the treatment of food allergy in the 6 months prior to screening visit * inhalant allergent immunotherapy that has not yet reached maintenance dosing * inability to discontinue antihistamines for skin testing, OFC * any systemic therapy which in the judgment of the investigator could be immunomodulatory in the 12 months prior to visit 1 (xolair, rituximab, chronic steroids, etc) * investigational drug use 90 days prior to visit 1 or intention to use during study period * the presence of any medical condition that the investigator deems incompatible with participation in the trial. * unable to understand and speak English