Early Markers of Radiation-Induced Cardiac Injury in Hodgkin Lymphoma Treated With Radiation Therapy

University of Florida5 enrolled

Overview

The purpose of this study is to evaluate if radiation and chemotherapy treatment cause cardiac abnormalities among survivors of Hodgkin's lymphoma.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Hodgkin's Lymphoma

Interventions

Cardiac Magnetic Resonance ImagingPROCEDURE

A cardiac MRI will be performed.

EchocardiogramPROCEDURE

An echocardiogram will be performed for the following information: M-mode, two-dimensional, Doppler blood flow measurements, and longitudinal strain and strain rate imaging

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Completed radiation and chemotherapy treatment for Hodgkin lymphoma involving the mediastinum. * Patient must be ≥ 18 years at time of consent. Exclusion Criteria: * Pregnant women at time of Cardiac MRI * Contraindications to Cardiac MRI (contrast allergy, metal implants, medical devices) * Glomerular filtration rate (GFR) \< 30, unless approved by Radiologist (UF Health Jacksonville Radiology Policy: Administration of Gadolinium-Based Contrast Agents).

Locations (1)

University of Florida Health Proton Therapy Institute

Jacksonville, Florida, United States

Outcomes

Primary Outcomes

Cardiac Abnormalities As Measured By Cardiac MRI

Time frame: Day 1

Cardiac Abnormalities As Measured By Echocardiogram

Time frame: Day 1

Data from ClinicalTrials.gov

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