This is a validation study comparing a pulse wave based algorithm for the detection of coronary artery disease with parameters from coronary angiography, echocardiography and cardiogoniometry.
The study will validate a pulse wave based algorithm for the detection of coronary artery disease (CAD) with parameters from standard methods. Subjects will be patients admitted to coronary angiography due to suspected CAD. Pulse wave signals will be analyzed according to novelly established algorithm regarding the presence of CAD and/or myocardial ischemia. These results be compared to the diagnoses made by coronary angiography (primary endpoint): presence of minimum one coronary artery stenose \>=50%. For secondary analyses, results will be compared to parameters form echocardiography and cardiogoniometry.
Study Type
OBSERVATIONAL
Enrollment
156
Validation of a diagnostic algorithm used to detect coronary artery disease and/or myocardial ischemia based on pulse wave analyses.
Marcus Dörr
Greifswald, Germany
Presence of CAD - angio (minimum 1 stenosis >=50%)
Presence of CAD in coronary angiography: minimum 1 stenosis \>=50%
Time frame: 1 day
Presence of CAD number - angio (Number of coronary vessels with at least 1 stenosis >=50% in coronary angiography)
Number of coronary vessels with at least 1 stenosis \>=50% in coronary angiography
Time frame: 1 day
Wall motion abnormality - echo (Presence of wall motion abnormality in at least 1 segment (2D echocardiography)
Presence of wall motion abnormality in at least 1 segment (2D echocardiography)
Time frame: 1 day
Wall motion index - echo (Wall motion index (2D and 3D echocardiography)
Wall motion index (2D and 3D echocardiography)
Time frame: 1 day
Global longitudinal strain (2D and 3D echocardiography)
Global longitudinal strain (2D and 3D echocardiography)
Time frame: 1 day
Abnormal cardiogoniometry
Abnormal results of cardiogoniometry
Time frame: 1 day
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