Prognostic Factors in Epiretinal Membrane Surgery

Centre Hospitalier Universitaire Dijon142 enrolled

Overview

Retrospective interventional case series study reporting preoperative clinical and anatomical factors associated with visual recovery 1 year after combined cataract and idiopathic epiretinal membrane surgery. Age, duration of symptoms, and preoperative best corrected visual acuity appeared to be reliable prognostic factors. Combining these factors with analysis of the photoreceptors' inner and outer segments junction in spectral-domain optical coherence tomography provides a predictive score to estimate individual chances of good visual recovery

Study Type

OBSERVATIONAL

Enrollment

142

Conditions

Epiretinal Membranes

Interventions

a combined cataract and ERM surgeryPROCEDURE

All patients underwent a combined cataract and ERM surgery owing to visual impairment or disabling metamorphopsia. A complete ophthalmological examination was performed before and at 1,6, and 12 months after the surgery, including best corrected visual acuity with Snellen charts converted into the logarithm of the minimum angle of resolution, slit-lamp biomicroscopy, indirect fundus, and macular optical coherence tomography

Eligibility

Sex: ALLMin age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * symptomatic idiopathic epiretinal membrane operated on between April 2009 and September 2012 at the university hospital of Dijon, France. * All patients signed informed consent for the surgical procedure. Exclusion Criteria: * Patients were excluded if they presented any cause of secondary epiretinal membrane (including diabetic retinopathy, vein occlusion, ocular inflammation, retinal detachment, or previously vitrectomized eye), high myopia (axial length ≥ 26 mm or spherical equivalent ≥ 6 diopters), severe media opacities with weak SD-OCT signal strengths, or any macular or optic nerve disease. Patients with a follow-up of less than 12 months were excluded and only one eye was included in those with bilateral epiretinal membranes.

Outcomes

Primary Outcomes

Best corrected visual acuity

Best corrected visual acuity 1 year after the surgery, and preoperative factors associated with this visual outcome (age, duration of symptoms, initial best corrected visual acuity, and optical coherence tomography findings)

Time frame: 1 year after the surgery

Secondary Outcomes

To set up a predictive score for a >= 20/20 best corrected visual acuity

To set up a predictive score for a \>= 20/20 best corrected visual acuity, 1year after a combined cataract and epiretinal membrane surgery

Time frame: 1 year after the surgery

Data from ClinicalTrials.gov

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