The purpose of this study is to explore the effectiveness of an internet-delivered cognitive control training as a preventive intervention for remitted depressed patients.
Prospective studies have linked impaired cognitive control to increased cognitive vulnerability for future depression. Importantly, experimental studies indicate that cognitive control training can be used to reduce rumination and depressive symptomatology in MDD samples. Furthermore, studies exploring the potential of cognitive control training in at-risk undergraduate students indicate that cognitive control training has beneficial effects on rumination, an important vulnerability factor for depression. Provided that remitted depressed patients form a high-risk group for developing future depressive episodes, the current study will explore whether internet-delivered cognitive control training can be used to reduce vulnerability for future depression in remitted depressed patients. The investigators will explore effects on depressive symptomatology, (mal-)adaptive emotion regulation (directly following training and at 3 months follow-up), and indices of functioning (at 3 months follow-up).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
68
10 adaptive Paced Auditory Serial Addition Task (PASAT) sessions, 400 trials each
10 low cognitive load sessions, 400 trials each
Ghent University
Ghent, Oost-Vlaanderen, Belgium
Change in depressive rumination from baseline to the post-training assessment and follow-up (RRS)
Assessed using the Ruminative Response Scale (RRS)
Time frame: baseline, 2 weeks, 3 months
Change in depressive symptomatology from baseline to the post-training assessment and follow-up (BDI-II)
Assessed using the Beck Depression Inventory (BDI-II)
Time frame: baseline, 2 weeks, 3 months
(mal-)Adaptive cognitive emotion regulation (CERQ)
Assessed using the Cognitive Emotion Regulation Questionnaire (CERQ)
Time frame: baseline, 2 weeks, 3 months
Quality of Life (QLDS)
Assessed using the Quality of Life in Depression Scale (QLDS)
Time frame: baseline, 3 months
Disability (WHODAS 2.0)
Assessed using the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0)
Time frame: baseline, 3 months
Resilience (RS)
Assessed using the Resilience Scale (RS)
Time frame: baseline, 3 months
Remission from depression (RDQ)
Assessed using the Remission of Depression Questionnaire (RDQ)
Time frame: baseline, 3 months
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