Assess the impact in body composition and handgrip strength of the nocturne supplementation by a month with BCAA (Enterex hepatic in patients awaiting liver transplantation)
Clinical trial study was make, data were obtained from people awaiting liver transplantation and with at least a criteria of protein/energy malnutrition (fase angle \< 5.4°, subjective global assessment B or C and/or handgrip strength \< 30 in men and \< 20 in women). The investigators make them body composition assessment (weight, height, body mass index \[BMI\], mean arm circumference \[MAC\], muscle arm area \[MAA\], tricipital skinfold, Dual X ray absorptiometry \[fat mass and fat free mass\]) and handgrip strength at beginning and after 30 days of nocturne supplementation with BCAA and standardized diet (35-40 Kcal, 55% carbohydrates, 25% lipids and 20% proteins).
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
38
The patients will drink a Enterex Hepatic bag (500 Kcal, 18.6g of proteins of which 8.63g are branched chain amino acids, 71.7g of carbohydrates and 15.4g of lipids) during late evening (after 19:00 hours) in comparison with the late evening snack group which will eat a snack based in food with the next nutrimental facts (480 Kcal, 19g of proteins based in casein and vegetables sources, 17g of lipids and 63g of carbohydrates) during the same schedule that intervention group.
Instituto Nacional de ciencias Médicas y Nutrición Salvador Zubirán
Mexico City, Mexico City, Mexico
RECRUITINGChange in Body Composition
The body composition will be measured with air displacement pletismografy through Bodpod the results will be expressed in percentaje of fat mass and fat free mass.
Time frame: Basal and 30 and 60 days after intervention.
Change in Mid arm muscle area
Estimation of muscle area of the no dominant arm using the formula \[(MAMA - (π x PT))2 / 4 π \] \- 10 in men and -6.5 in women, the result is expressed in cm2.
Time frame: Basal and 30 and 60 days after intervention.
Change in Quality of life
It will be measured by the questionnaire SF-36 that is a generic scale providing a health profile and is applicable for both, patients and general population; the results that the 36 questions divided in 8 dimensions. The patients answers will be transformed to a numeric scale: since 0 (worst) to 100 (better)
Time frame: Basal and 30 and 60 days after intervention.
Change in Fase angle.
vectorial sum of the resistance and reactance result in the impedance, and the angle that is formed is called the fase angle; this is obtain through a impedanciometre, the measure is expressed in grades.
Time frame: Basal and 30 and 60 days after intervention.
Change in Handgrip strength.
Handgrip strength of the no dominant hand will be measured by a hand dynamometer in kilograms/Force
Time frame: Basal and 30 and 60 days after intervention.
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