Observational Retrospective Study on Treatment and Outcomes in Patients With Low-grade Serous Ovarian Cancer

National Cancer Institute, Naples150 enrolled

Overview

The purpose of this study is to retrospectively evaluate treatments and outcomes of patients with low grade serous ovarian carcinomas in Italy.

Study Type

OBSERVATIONAL

Enrollment

150

Conditions

Low-grade Serous Ovarian Carcinoma Recurrent Invasive Borderline Serous Ovarian Cancer

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis low-grade serous ovarian carcinoma * OR invasive recurrence after surgical resection of borderline serous ovarian carcinoma * Availability of archival tumor specimen (paraffin embedded block) for central analysis and evaluation for mutations * Age \> 18 years * Signed informed consent Exclusion Criteria: * High-grade serous, mucinous, endometrioid, or any other non-low-grade serous ovarian carcinoma * Unavailability of archival tumor specimen

Locations (1)

Istitute Nazionale Tumori - Fondazione G. Pascale

Napoli, Italy

RECRUITING

Outcomes

Primary Outcomes

risk of recurrence in patients with low-grade serous ovarian carcinoma

Time frame: two years

number of patients with objective tumor response after receiving chemotherapy

Time frame: 6 months

number of patients with objective tumor response after receiving hormone therapy

Time frame: 6 months

number of patients with objective tumor response after receiving combination hormonal and chemotherapy

Time frame: 6 months

progression free survival

Time frame: 2 years

overall survival

Time frame: 5 years

Central Contacts

Francesco Perrone, MD PhD

CONTACT

+39 081 5903571 datamanager@usc-intnapoli.net

Teresa Ribecco, PhD

CONTACT

+39 081 5903619 teresa.ribecco@usc-intnapoli.net

Data from ClinicalTrials.gov

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