The Dynamic Effect of Non-cytochrome P450 Isoenzyme 3A4（CYP3A4）-Metabolized and Cytochrome P450 Isoenzyme 3A4（CYP3A4）-Metabolized Statins on Clopidogrel Resistance in Patients With Cerebral Infarction

Inclusion Criteria: * The patient must have signed an informed consent document indicating that they understand the purpose of and procedures required for the study and are willing to participate in the study. * Age \<85 years and \>45 years ,Male or female. * The patient have been Cerebral infarction for one month. * national institutes of health stroke scale（NIHSS）score ≤23 points. * Blood Platelet count greater than 150×10\^9／L,and Less than 500×10\^9／L. * The patient never do not taking aspirin 、dipyridamole、clopidogrel,or the patient had been taken these anti-platelet drugs but has been discontinued for two weeks at least. * The patient never do not taking Statins or the patient have been stop taking statins 2 weeks for two weeks. Exclusion Criteria: * Allergic constitution , or allergic to the composition of the drugs in this study. * national institutes of health stroke scale（NIHSS） score \>23 points. * Atrial fibrillation and other cardiogenic cerebral embolism. * Patients who were undergone surgery and trauma (including fractures) within the past three month. * Patients with known dysfunction of vital organs or suffered from Serious cardiovascular disease ，or coagulation disorders. * The patient took Proton pump inhibitors recently. * The history of data collection and the follow-up process can not be saved.