Intensive Care Unit (ICU) acquired pneumonia, including ventilator-associated pneumonia, is a frequently occurring health-care associated infection, which causes considerable morbidity, mortality and health care costs. Important pathogens causing ICU pneumonia are Staphylococcus aureus and Pseudomonas aeruginosa. The epidemiology of ICU pneumonia and patient-related and contextual factors is not fully described, but is urgently needed to support the development of effective interventions.
Study Type
OBSERVATIONAL
Enrollment
2,031
A risk prediction model will be developed to assess which risk factors are associated with the development of ICU pneumonia during ICU stay
UMC Utrecht
Utrecht, Netherlands
Incidence of S. aureus ICU pneumonia
Time frame: date of ICF until ICU discharge (on average 7 days after ICF)
Incidence of P. aeruginosa ICU pneumonia
Time frame: date of ICF until ICU discharge (on average 7 days after ICF)
Prevalence of S. aureus / P. aeruginosa colonization
Time frame: at ICU admission
Incidence of all cause ICU pneumonia
Time frame: date of ICF until ICU discharge (on average 7 days after ICF)
Incidence of S. aureus ICU pneumonia stratified by MRSA vs. MSSA
Time frame: date of ICF until ICU discharge (on average 7 days after ICF)
Incidence of P. aeruginosa ICU pneumonia stratified by MDR-PA vs. S-PA
Time frame: date of ICF until ICU discharge (on average 7 days after ICF)
Incidence of ICU bacteremia per etiologic agent (in case of S. aureus and/or P. aeruginosa and for all clinically relevant other pathogens)
Time frame: date of ICF until ICU discharge (on average 7 days after ICF)
All-cause mortality
Time frame: date of ICF until ICU discharge (on average 7 days after ICF)
All-cause mortality
Time frame: At day 30 after ICU admission
All-cause mortality
Time frame: At day 90 after ICU admission
Time to S. aureus ICU pneumonia
Time frame: day of ICU admission until ICU discharge (on average 7 days after ICU admission)
Time to P. aeruginosa ICU pneumonia
Time frame: day of ICU admission until ICU discharge (on average 7 days after ICU admission)
Time to all cause ICU pneumonia
Time frame: day of ICU admission until ICU discharge (on average 7 days after ICU admission)
Time to all cause ICU bacteremia
Time frame: day of ICU admission until ICU discharge (on average 7 days after ICU admission)
Time to death of any cause
Time frame: day of ICU admission until day 90 or ICU discharge, whichever comes first
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