The purpose of this study is to estimate the clinical value of contrast-enhanced ultrasound in percutaneous biopsy for liver occupied lesion.
The patients with liver neoplasms who need receive percutaneous biopsy were randomized into contrast-enhanced ultrasound(CEUS) group and conventional ultrasound(US) group.The aims include: 1. Comparison the diagnostic accuracy rate, specificity and sensitivity between CEUS and US group. 2. Comparison the diagnostic accuracy rate specificity and sensitivity between smaller(\<3cm) and larger(≥3cm) nodule group. 3. To explore operating strategy of contrast-enhanced ultrasound guided biopsy. 4. To evaluate economic efficiency of contrast-enhanced ultrasound guided biopsy compared with conventional ultrasound guided biopsy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
2,088
Biopsy was operated under contrast-enhanced ultrasound-guided.
Biopsy was operated under conventional ultrasound-guided.
Beijing Cancer Hospital
Beijing, Beijing Municipality, China
RECRUITINGdiagnostic accuracy
diagnostic accuracy=（true positive+ ture negative)/number of parcitipants
Time frame: 12 months
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