Immunity Improvement Effect of Ulmus Macrocarpa Water Extract in Adults

Pusan National University Hospital58 enrolled

Overview

This randomized, placebo-controlled, double-blind study evaluates the efficacy and tolerability of Ulmus macrocarpa water extract for immunity improvement in relatively healthy adults. 58 subjects received 500 mg of Ulmus macrocarpa water extract per day or a placebo for 4 weeks.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

TRIPLE

Enrollment

Conditions

Healthy

Interventions

Ulmus macrocarpa water extractDIETARY_SUPPLEMENT

Eligibility

Sex: ALLMin age: 19 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * subject has peripheral white blood cells between 4,000/Ul and 8,000/Ul Exclusion Criteria: * History of renal disease * History of diabetes mellitus * History of immune disease

Outcomes

Primary Outcomes

serum natural killer cell activity

Time frame: 1 month

Secondary Outcomes

peripheral white blood cell

Time frame: 1 month

serum tumor necrosis factor-alpha level

Time frame: 1 month

serum interferon-gamma

Time frame: 1 month

serum interleukins(1betta, 2,4,8,10, and 12)

Time frame: 1 month

Data from ClinicalTrials.gov

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