This Phase 1a, single center, open-label, repeat dose study will evaluate the safety, efficacy, and Pharmacokinetics of ascending doses of OBP-801 in patients with advanced solid tumors.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
17
OBP-801 will be administered IV
Barbara Ann Karmanos Cancer Institute
Detroit, Michigan, United States
Maximum Tolerated Dose
Time frame: 6 weeks
Pharmacokinetic (PK) profile; AUC, Cmax, and t1/2
Time frame: 4 weeks
Objective Response (OR)
Time frame: 22 weeks
Durability of Objective Response (DOR)
Time frame: 22 weeks
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