Vitamin D Status and Immune Function

Bangor University264 enrolled

Overview

The purpose of this study is to examine the relationship between Vitamin D status and immunity.

Vitamin D is mainly obtained from the sun and follows a seasonal pattern, with Vitamin D levels peaking in summer and reaching a trough during winter. Vitamin D deficiency is associated with impaired immunity. However, knowledge of Vitamin D deficiency with in vivo immunity is limited. This observational study aims to investigate the relationship between Vitamin D status and the in vivo immunity.

Study Type

OBSERVATIONAL

Enrollment

264

Conditions

Vitamin D Deficiency

Interventions

In vivo immunity modelOTHER

A measure of in vivo immune function.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Passed medical assessment by medical doctor * Passed audio test (this is part of medical assessment) * Met physical fitness requirements Exclusion Criteria: • Medically deferred by medical doctor

Locations (1)

Infantry Training Centre

Catterick, North Yorkshire, United Kingdom

Outcomes

Primary Outcomes

Vitamin D measured by liquid chromatography tandem mass spectroscopy

Circulating 25-hydroxy-vitamin D

Time frame: Up to 20 months

Secondary Outcomes

Immune function measured by analytic biochemistry assay

In vivo immune measure

Time frame: Up to 20 months

Data from ClinicalTrials.gov

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