Prevention of Recurrence of Crohn's Disease by Fecal Microbiota Therapy (FMT)

Inclusion Criteria (Patients): * Adults (age \> 18) * Confirmed diagnosis of Crohn's disease (CD), based on endoscopy, histology and imaging (confirmed by Study PI for each site) * Ileo-cecal resection or terminal ileal resection for CD within 30 days prior to enrollment * Resection margins \& anastomosis free of active inflammation based on histology and surgical description (confirmed by Study PI for each site) * No therapy to prevent post-operative recurrence of CD. A 30-day wash-out period for anti- tumor necrosis factors (TNF)s, thiopurines, antibiotics will be required prior to enrollment. Exclusion Criteria (Patients): * Diagnosis of indeterminate colitis * Women who are pregnant or nursing * Patients who are unable to give informed consent * Patients who are unable or unwilling to undergo colonoscopy with moderate sedation (\>ASA class II) * Patients who have previously undergone FMT * Patients who have a confirmed malignancy or cancer * Participation in a clinical trial in the preceding 30 days or simultaneously during this trial * Probiotic use within 30 days of start date * Decompensated cirrhosis * Congenital or acquired immunodeficiencies * Chronic kidney disease as defined by a GFR \<60mL/min/1.73m2 44 * History of rheumatic heart disease, endocarditis, or valvular disease due to risk of bacteremia from colonoscopy