A Phase 3 Study of SYM-1219 Treatment of Women and Post-Menarchal Adolescent Girls With Bacterial Vaginosis

Inclusion Criteria: * Are premenopausal adult females or post menarchal adolescent girls ≥12 years of age in good general health * Have a clinical diagnosis of bacterial vaginosis, defined as having all of the following criteria: * Off-white (milky or gray), thin, homogeneous vaginal discharge * Vaginal pH ≥ 4.7 * Presence of Clue cells of ≥ 20% of the total epithelial cells on microscopic examination of the vaginal saline wet mount * A positive 10% KOH Whiff test * Have a Gram stain slide Nugent Score ≥ 4 at the Baseline Visit (Day 1) Exclusion Criteria: * Are pregnant, lactating, or planning to become pregnant during the study * Are menstruating or have vaginal bleeding at the Baseline Visit (Day 1) * Are suspected clinically (or confirmed diagnostically) of having alternative causes of vaginal symptoms including candidiasis, Chlamydia trachomatis, Trichomonas vaginalis, Neisseria gonorrhoeae or Herpes simplex * Have received antifungal or antimicrobial therapy (systemic or intravaginal) within 14 days prior to the Baseline Visit (Day 1)