The primary objective of this study is to investigate whether the dual transcranial direct current stimulation(tDCS) improves the swallowing function of stroke patients.
120 patients were recruited and randomized to receive either real or sham-tDCS. Real experimental groups were divided into three types; Anode-Anode dual stimulation group, Anode-Cathode dual stimulation group, Single stimulation group. 20-minutes session of the stimulation were applied 5 times a weeks for 2 weeks at pharyngeal motor cortex of affected or non-affected site. The patients were evaluated at baseline, immediately and 2 weeks after tDCS.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
120
Transcranical direct current stimulator (Neuroconn GmbH, Ilmenau, Germany) approved by Conformity European as safe treatment device for stroke patients tDCS intervention\] * Intensity: 1.5mA for 20min Device: Neuroconn GmbH, Ilmenau, Germany * Stimulation site \<Experimental group\> * Anode-Anode dual stimulation group Anode: affected pharyngeal motor cortex / Cathode: affected supraorbit Anode: non-affected pharyngeal motor cortex / Cathode: non-affected supraorbit * Anode-Cathode dual stimulation group Anode: affected pharyngeal motor cortex Cathode: non-affected pharyngeal motor cortex * Single stimulation group Anode: affected pharyngeal motor cortex Cathode: non-affected supraorbit \<Control group\> Sham stimulation
Pusan National University Yangsan Hospital
Yangsan, South Korea
RECRUITINGChange in Dysphagia Outcome and Severity Scale(DOSS) from video fluoroscopic swallowing study(VFSS)
Time frame: up to 60 sec
American Speech-LanguageHearing Association(ASHA)-Norms
Change in swallowing function
Time frame: up to 2 weeks after tDCS
Korean Version of Modified Barthel Index(K-MBI)
Change in activity of daily living
Time frame: up to 2 weeks after tDCS
Dysphagia Outcome and Severity Scale(DOSS) from video fluoroscopic swallowing
Change in swallowing function
Time frame: 2 weeks after tDCS
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