The purpose of this study is to evaluate the effects of long-term tamponade with silicone oil on retinal saturation with Oxymap.
Silicone oil is the first choice treatment for long-term vitreous replacement in complicated cases of retinal detachment. However, it will cause various problems for permanent tamponade, such as keratopathy, glaucoma, cataracts, and silicone oil emulsification3. In addition, silicone oil has the potential to cause retinal toxicity. Moreover, the gravity and mechanical pressure of the silicone oil on the retina may influence retinal blood flow and, and the presence of silicone oil in the vitreous cavity may block the oxygen exchange between the retinal surface and the vitreous humor, resulting in the metabolic disturbance of the retina. In this study, the investigators utilized a noninvasive measurement (Oxymap, Reykjavik, Iceland) to evaluate the effect of silicone oil tamponade on oxygen saturation and diameter in retinal vessels in complicated retinal detachment cases.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
49
The patients in each group will receive the same procedure of silicone oil removal.
Zhongshan Ophthalmic Center
Guangzhou, Guangdong, China
The changes from baseline in the retinal oxygen saturation by Oxymap at 2 months
Time frame: 1 day before silicone oil removal and 2 months after silicone oil removal.
The changes from baseline in the retinal vessel width by Oxymap at 2 months
Time frame: 1 day before silicone oil removal and 2 months after silicone oil removal.
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