Severe brain-injured patients require prolonged mechanical ventilation. Weaning these patients from mechanical ventilation is challenging. During neurologic recovery, brain injured patients usually present satisfactory respiratory autonomy. However, the exact timing of extubation is unknown and is frequently delayed because of potential inhalation. To date, there are no clinical signs available in the current literature that can help the attending physician in the decision-making process of extubation in brain-injured-patients
Study Type
OBSERVATIONAL
Enrollment
450
A code will be applied to each patient included. Medical data such as demography, ISS, clinical exam at time of extubation, extubation failure, tracheotomy, will be collected during ICU stay.
Angers University Hospital
Angers, France
Nantes University Hospital
Nantes, France
Rennes University Hospital
Rennes, France
Extubation failure
Extubation failure is regarded as the need of intubation in the 48 hours following extubation Establish clinial signs before extubation that can predict extubation failure Realization of a systematic clinical examination by the attending physician before performing extubation in severe brain-injured patients
Time frame: In the 48 hours following extubation
Impact of extubation failure
Impact of extubation failure on * Duration of mechanical ventilation * Length of ICU stay * Mortality Describing reasons
Time frame: Median 14 days after Intensive Care Unit (ICU) admission
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