Mucosal Microbiome in Human Gastric Intestinal Metaplasia and Duodenal Tissue.

N/AUnknownNCT02428426

Shandong University20 enrolled

Overview

To investigate the mucosal microbiome in human gastric intestinal etaplasia and duodenal tissue.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Mucosal Microbiome Gastric Intestinal Metaplasia Duodenum

Interventions

endomicroscopy, targeted biopsy and 16s rRNA gene sequencingOTHER

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients scheduled for gastroendoscopy examination Aged between 18 and 80 years old Exclusion Criteria: * Antibiotic, probiotic or prebiotic usage within 2months,gastric inhibitor usage within 1 month Esophageal, gastric or duodenal cancer or other malignancy History of upper GI tract surgery Coagulopathy or bleeding disorders Allergy to fluorescein sodium Pregnant or breast-feeding (for females) Impaired renal function

Locations (1)

Department of Gastroenterology, Qilu Hospital, Shandong University

Jinan, Shandong, China

RECRUITING

Outcomes

Primary Outcomes

The operational taxonomy units in gastric Intestinal Metaplasia and and Duodenal mucosal microbiome

Time frame: 6 months

Central Contacts

li yanqing, PhD,MD

CONTACT

86-531-82169236 liyanqing@sdu.edu.cn

Data from ClinicalTrials.gov

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