Evaluate the effects of topical C-82 in a psoriasis plaque test.
The primary objective of this trial is to evaluate antipsoriatic efficacy of the C-82 topical gel compared with vehicle by measurement of the thickness of the Echo Lucent Band (ELB) of the psoriatic infiltrate using 20 MHz sonography. To gain additional information about possible efficacy the change of the test fields compared to untreated plaque will be clinically assessed by visual scoring.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
14
Unnamed facility
Schwerin, Germany
antipsoriatic efficacy of the C-82 topical gel compared with vehicle by measurement of the thickness of the Echo Lucent Band (ELB) of the psoriatic infiltrate
Time frame: day 12
antipsoriatic efficacy compared to control by clinical assessment using a 5-point score.
Time frame: Day 8 & Day 12
number of subjects with adverse events
Time frame: daily through Day 12
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