Coronary artery disease is a common and serious disease, the leading cause of death worldwide. Obstructive sleep apnea syndrome (OSAS) is common and often under-diagnosed in coronary artery disease where it could be involved in the pathophysiology and perhaps prognosis. The entanglement of the two pathologies is actually quite well known, in particular the consequences of one over the other just beginning to be studied. Understanding the pathophysiology through new imaging modalities should improve the management of patients to propose new approaches. "SAS-IDM" is an interventional and prospective study conducted at the University Hospital of Montpellier. Patients will be divided in three groups depending of the results of the polysomnography: 1/ AHI \< 5/h: normal, without OSA ; 2/ 5/h ≤ AHI \< 30/h: mild or moderate OSA ; 3/ IAH ≥ 30/h: severe OSA. A treatment by CPAP will be proposed to patients of the group "severe OSA".
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
67
Hôpital Arnaud de Villeneuve - CHU de Montpellier
Montpellier, France
Changes in diameter (mm) and end diastolic and systolic LV volumes (mL) at 6 months of acute MI among a group of patients without OSA (AHI <5 / h) and a group of patients with mild to moderate OSA (AHI between 5 and 30 / h)
Time frame: 6 months of acute MI
Transmural enhancement (%) at 6 months of acute MI among a group of patients without OSA (AHI <5 / h) and a group of patients with mild to moderate OSA (AHI between 5 and 30 / h)
Time frame: 6 months of acute MI
Thickness of the LV wall (mm) at 6 months of acute MI among a group of patients without OSA (AHI <5 / h) and a group of patients with mild to moderate OSA (AHI between 5 and 30 / h)
Time frame: 6 months of acute MI
Presence no reflow at 6 months of acute MI among a group of patients without OSA (AHI <5 / h) and a group of patients with mild to moderate OSA (AHI between 5 and 30 / h)
Time frame: 6 months of acute MI
The difference in cardiac remodeling in cardiac MRI at 6 months between the three diagnostic categories
Time frame: At 6 months after inclusion
The difference in cardiac remodeling in cardiac MRI between the date of inclusion and 6 months between diagnostic categories.
Time frame: Between the date of inclusion and 6 months
The difference of left ventricular remodeling in cardiac MRI between the date of inclusion and 6 months in the severe OSA group based on the assumption (good compliance and effectiveness of PPC or not)
Time frame: Between the date of inclusion and 6 months
The occurrence of cardiovascular events during the first year following the IDM depending on the initial AHI index.
Time frame: Between the date of inclusion and one year
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