Remote Ischemic Conditioning in Patients With Ulcerative Colitis

Inclusion Criteria: * Age:≥18 years * Verified ulcerative colitis diagnosis according to clinical, endoscopic and histological standard criteria. * Diagnosis of ulcerative colitis established for at least 6 months * Moderate active ulcerative colitis, total Mayo score \> 6 * Endoscopic subscore activity grade ≥1 * Written informed consent Exclusion Criteria: * Pancolitis or acute severe ulcerative colitis requiring immediate treatment * Need for admission due to active ulcerative colitis * Ulcerative colitis with systemic symptoms (abdominal pain, fever \> 37.5 degrees, weight loss exceeding 3 kilograms). * Patient with anemia (Haemoglobin \< 8.3 mmol/l for males and \< 7.3 mmol/l for females). * Patient with ostomy or pouch. * The patient has had a bowel resection (except appendectomy) * The patient has constipation and/or another known bowel condition than ulcerative colitis such as IBS. * The patient has diabetes. * Regular intake of acetylsalicylic acid or NSAIDs * The patient cannot understand the information material. * The patient has had colon cancer, dysplasia or adenomatous polyps in the colon during the recent 5 year * The patient is in a poor general condition. * The patient has had a food poisoning within the last three months. * The patient is pregnant at the time of inclusion or has planned pregnancy during the period of study. * The patient is in medical treatment with cyclosporine at the beginning of the run in period. * Treatment for ulcerative colitis treatment has been changed within two weeks before the first day in the run in period * The patient has commenced treatment with azathioprine, 6-mercaptopurine or methotrexate within 12 weeks before the first day in the run in period. * The patient has commenced treatment with TNF-α inhibitors within 12 weeks before the first day of the run in period. * The patient suffers from coeliac disease or lactose intolerance. * Antibiotic treatment within two weeks before the first day of the run in period. * Patient has any medical, surgical condition that excludes the use of RIC.