The investigators designed a prospective randomized study to compare the conventionally used sedative drug propofol with a latest alternative dexmedetomidine (DEX), in patients with end-stage renal disease undergoing arteriovenous fistula (AVF) surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
48
Propofol was administered at 1 mg/kg over a 10-min period followed by a continuous infusion at a rate of 1-1.5 mg/kg/h until the the begining of skin suture (n=24).
DEX was administered at 1 μg/kg over a 10-min period followed by a continuous infusion at a rate of 1-1.5 μg/kg/h until the begining of skin suture (n=24).
Baskent University School of Medicine Adana Research and Teaching Center
Adana, Turkey (Türkiye)
RECRUITINGThe incidence of adverse effects such as respiratory and hemodynamic events
Time frame: up to 24 hours postoperative
The sedation onset time with using BIS and recovery times during the procedure.
Time frame: up to 24 hours postoperative
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