The Effect of Supplementation With Species of Lactobacillus on Anthropometric Measurements

Urmia University of Medical Sciences72 enrolled

Overview

The investigators aimed to study the effect of supplementation with species of Lactobacillus on anthropometric measurements, body composition, appetite and serum lipid profile in overweight and obese adults

The Objective of This Study was Evaluating the Effect of supplementation with Species of Lactobacillus on anthropometric measurements include weight, waist and hip circumference , body composition include body fat and muscle percent, appetite measured by visual analogues scale and serum lipid profile in overweight and obese adults.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Overweight and Obesity

Interventions

Species of LactobacillusDIETARY_SUPPLEMENT

2 capsule a day Lactofem probiotics containing Species of Lactobacillus

lactoseDIETARY_SUPPLEMENT

2 capsule a day containing lactose

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18-65 years * BMI more than 25 Kg/m2 Exclusion Criteria: * taking drugs that could affect weight change, including anti-diabetic drugs, lipid lowering drugs * endocrine,cardiovascular, thyroid, or chronic liver disease. * had received surgery to reduce weight * taking probiotics or antibiotics within one month * Pregnancy or lactation or menopause * A history of cancer * Heart disease - cardiovascular, pulmonary, renal and diabetes * A history of autoimmune disease * Taking certain medications such as blood pressure control, statins, insulin sensitivity enhancers * weight change over five percent within three months * change in activity or diet habit

Locations (1)

sardrood Clinic

Tabriz, Iran

Outcomes

Primary Outcomes

weight change

Time frame: Change from Baseline in body weight at 12 weeks

Secondary Outcomes

defecation

Bristol stool scale (BBS)

Time frame: Baseline,4 weeks, 8 weeks, 12 weeks

blood pressure

include systolic and diastolic blood pressure

Time frame: Baseline,12 weeks

Anthropometric Measurement BMI

Body Mass Index (BMI) kg/m2

Time frame: Baseline,4 weeks, 8 weeks, 12 weeks

Anthropometric Measurement WC

waist circumference (WC) measures by "cm"

Time frame: Baseline,12 weeks

Anthropometric Measurement HC

hip circumference (HC) measures by "cm"

Time frame: Baseline,12 weeks

Appetite

numeric analogue Scale (NAS) mm

Time frame: Baseline,4 weeks, 8 weeks, 12 weeks

Anthropometric Measurement WHR

waist to hip ratio (WHR)

Time frame: Baseline,12 weeks

mid arm circumference Measurement

Time frame: Baseline,12 weeks

Serum Lipid Profile

Time frame: Baseline,12 weeks

Data from ClinicalTrials.gov

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