There is preliminary evidence that a dynamic T2 Preparations Puls sequence by cardiac magnet resonance imaging can differentiate between oxygenated and deoxygenated blood. In adult patients with inborn heart defects this has not yet been researched. Therefore,patients with ventriculoperitoneal shunt, septal and atrio-septal shunt should be examined. Also, patients with chronic obstructive pulmonary disease should be examined. The aim of this study is the validation of a novel magnet resonance sequence in terms of a distinction of oxygenated blood to deoxygenated blood in comparison to invasive method of measuring cardiac catheterization.
Study Type
OBSERVATIONAL
Enrollment
80
MRI
coronary angiography
University Hospital Duesseldorf
Düsseldorf, Germany
ventricular volumetry
ventricular volumetry by Cardiac Magnet Resonance Imaging using dynamic T2 Preparation Puls for arithmetical determination of end-systolic volume, end-diastolic volume, ejection fraction, stroke volume and myocardial weight
Time frame: baseline
oxygen partial pressure
Determination of oxygen partial pressure (pO2) during angiography
Time frame: baseline
carbon dioxide partial pressure
Determination of carbon dioxide partial pressure (pCO2) during angiography
Time frame: baseline
pH-value
Determination of pH-value od blood during angiography
Time frame: baseline
Blood gas analysis
Determination of base excess of blood during angiography
Time frame: baseline
Blood gas analysis
Determination of oxygen partial pressure (pO2), carbon dioxide partial pressure (pCO2), pH-value, base excess
Time frame: baseline
Major adverse cardiac events
Major adverse cardiac events: death, new indication for angiography, hospitalization
Time frame: 12 month after procedure
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