Trial of the TransMedics Organ Care System™ Liver For Preserving and Assessing Donor Livers for Transplantation

Inclusion Criteria: * Registered male or female primary Liver transplant candidate * Age ≥18 years old * Signed: written informed consent Exclusion Criteria: * Acute, fulminant liver failure; * Prior solid organ or bone marrow transplant; * Chronic use of hemodialysis or diagnosis of chronic renal failure, defined as chronic serum creatinine of \>3 mg/dl (\>265 mmol/L) for \>2 weeks and/or requiring hemodialysis; * Multi-organ transplant; * Ventilator dependent; * Dependent on \> 1 IV inotrope to maintain hemodynamics; * Malignancy excluding HCC; * Infection.