Pulse Pressure Variation Measured During Valsalva Maneuver to Predict Fluid Responsiveness Under Open-chest Condition

Samsung Medical Center55 enrolled

Overview

Pulse pressure variation (PPV) is a well-known dynamic preload indicator to predict fluid responsiveness. However, its usefulness in open-chest conditions has been equivocal. The investigators evaluated whether PPV measured during Valsalva maneuver can predict fluid responsiveness after sternotomy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Cardiac Surgical Procedures Thoracic Surgical Procedures Sternotomy

Interventions

Valsalva maneuverPROCEDURE

Valsalva maneuver was performed after sternotomy with the constant airway pressure of 30cmH2O for 2 breaths duration.

Fluid loadingOTHER

We record the cardiac index values before and after volume expansion with 6ml/kg of balanced crystalloid

Eligibility

Sex: ALLMin age: 20 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- Adult patients undergoing elective off-pump coronary arterial bypass grafting Exclusion Criteria: * Preoperative LV EF \<= 35% * Moderate or severe valvular heart disease * Cardiac arrhythmia * Intracardiac shunt * Severe renal or liver disease * Moderate to severe pulmonary hypertension (mean PAP \> 35 mmHg) * Patients with bullous lung disease or combined pneumothorax

Locations (1)

Samsung Medical Center

Seoul, South Korea

Outcomes

Primary Outcomes

Pulse pressure variation during Valsalva maneuver

Time frame: during Valsalva maneuver

Secondary Outcomes

Pulse pressure variation after sternotomy

Time frame: 5 min after sternotomy

Data from ClinicalTrials.gov

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