Recent meta-analyses suggest isometric resistance training (IRT) may be superior to aerobic exercise for lowering blood pressure. The investigators intend to conduct the largest, longest, prospective, double-blind randomized controlled trial using isometric resistance training to reduce blood pressure to reduce hypertension.
We are looking to assess the effect of isometric exercise on ambulatory blood pressure in participants aged 40-70 years who are either pre- or mild hypertensive; either un-medicated or taking medication to control their blood pressure. Our secondary aims are to examine whether the size of blood pressure change is different in those people taking or not taking anti-hypertensive medication, to determine the anti-hypertensive mechanism to IRT, and to establish rate of de-training effects after participants have ceased IRT.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
80
Isometric handgrip exercise using a hand dynamometer
UNE Exercise Physiology Lab
Armidale, New South Wales, Australia
Change in systolic and diastolic blood pressure
Time frame: Change measures: baseline and 12 weeks
Compare and contrast change in systolic and diastolic blood pressure of medicated and un-medicated participants
Time frame: Baseline and 12 weeks
Detraining effects, changes in systolic and diastolic blood pressure after cessation of Isometric Resistance Training
End of exercise protocol and 12 weeks after completion
Time frame: 12 weeks and 24 weeks
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