This is a prospective randomized controlled trial investigating the impact of educational bidirectional text message reminders on gluten free diet adherence among adolescents and young adults with celiac disease age 12-24. Participants will complete a series of online questionnaires assessing quality of life, patient activation, celiac symptoms, and self reported dietary adherence at the beginning and end of the study. Participants will also have their blood drawn to measure Tissue Transglutaminase IgA (TTG IgA) antibody and Deamidated Gliadin Peptide IgA (DGP IgA) at the beginning and end of the study. Lab draws can be done locally, and are at no cost to the participant. Patients are randomized to the intervention or control group based on enrollment TTG IgA. Intervention group receives 45 unique text messages over the 3 month study. A gift card is provided for participation in the study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
NONE
Enrollment
61
45 unique text messages designed by the Stanford Pediatric Gastroenterology physicians and nutritionists
Stanford University Pediatric Gastroenterology Department
Palo Alto, California, United States
Tissue Transglutaminase IgA (TTG IgA)
Percent change in TTG IgA for each participant pre and post study period
Time frame: 3 months
Deamidated Gliadin Peptide IgA (DGP IgA)
Percent change in DGP IgA for each participant pre and post study period
Time frame: 3 months
NIH-PROMIS quality of life score
Change in NIH-PROMIS quality of life questionnaire score pre and post study period
Time frame: 3 months
Patient Activation Measure (PAM) score
Change in Patient Activation Measure (PAM) questionnaire score pre and post study period
Time frame: 3 months
Patient-reported dietary adherence (CDAT) score
Change in patient-reported dietary adherence (CDAT) questionnaire score pre and post study period
Time frame: 3 months
Patient-reported celiac disease symptom measure (CDI) score
Change in patient-reported celiac disease symptom measure (CDI) questionnaire score pre and post study period
Time frame: 3 months
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