The purpose of this project is to study the effect of dietary supplementation with a natural health product (NHP) with a focus on its effects on its levels in breast milk.
The effect of oral cysteine on its levels in breast milk and plasma will be measured in breast feeding mothers. The investigators will not be studying tryptophan and tyrosine in this study. The title is an overview title left over from other past studies (but the investigators are only assessing cysteine at this time).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
24
The trade name is New Root Herbal Inc.
Research Imaging Centre, Centre for Addiction and Mental Health
Toronto, Ontario, Canada
Breast milk cysteine levels
measurement of amino acid before and after acute administration over a 10 hour period * The first visit would be the screening visit, which the subjects will be evaluated for general health status through a standardized health questionnaire. A urine test will be done in order to screen for any drug use. * On the second visit, each subject would be tested for plasma levels of the amino acid during the day. In addition breast milk will be tested in order to examine the effect of these supplements on the amino acid contents of the breast milk at few time points on both days.
Time frame: The main protocol occurs of 10 hours of time when the pharmacokinetics of the amino acid are measured.
plasma cysteine levels
These are the acute changes in plasma cysteine levels over 10 hours
Time frame: These are sampled over 10 hours before and after administration of cysteine
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