Iron deficiency anaemia is a major problem for women worldwide. Cereal foods are a major source of iron, but much of this is not bioavailability due to it being bound by the high amounts of phytate present in cereals. Destruction of phytate by the phytase enzyme can release iron and increase its bioavailability. In a human cell model of iron uptake, sourdough fermentation, which included activation of phytase, the enzyme that breaks down phyate, led to improved iron bioavailability. This clinical trial will attempt to demonstrate that this concept also works in humans
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Enrollment
102
Whole grain rye bread baked without sourdough fermentation (normal yeast-based fermentation)
Whole grain rye bread fermented with sourdough culture before baking
Serum ferritin
Time frame: 12 week values corrected for baseline
Serum transferrin receptor
Time frame: 12 week values corrected for baseline
Haemoglobin
Time frame: 12 week values corrected for baseline
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.