The purpose of this study is to evaluate the efficacy and safety of Z-215 (10 mg, 20 mg, 40 mg) , compared with Rabeprazole Sodium 10mg in patients with erosive esophagitis of Grade A to D as defined by the LA classification grading system.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
503
Z-215 10mg, capsules
Z-215 20mg, capsules
Z-215 placebo-matching capsules
Unnamed facility
Tokyo, Japan
Endoscopic Healing Rate Over 8 Weeks of Erosive Esophagitis
Time frame: 8 weeks
Endoscopic Healing Rate Over 4 Weeks of Erosive Esophagitis
Time frame: 4 weeks
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Rabeprazole Sodium 10mg tablets
Rabeprazole Sodium Placebo placebo-matching tablets