Sleep apnoea affects more than 20% of people over 65 years and is largely underdiagnosed. It does multiply tenfold the occurrence of vascular events, particularly stroke. While Continuous Positive Airway Pressure (CPAP) is currently the Gold standard treatment to prevent cerebrovascular and cardiovascular events, with a major clinical benefit, long term adherence to CPAP is a significant problem and search for alternative treatment is essential. The investigators hypothesize that long-term exercise training would allow to reduce significantly sleep apnoea syndrome severity. Thus, in this study, the investigators will compare evolution of Apnoea Hypopnea Index (AHI) in an exercise trained group performed through in a national based non-profit organization (Fédération Française d'éducation Physique et de Gymnastique Volontaire (FFEPGV)) using a medical established program (NeuroGyV) during nine months against a control group receiving only standard dietetic and physical activity counseling.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
96
CHU de Saint-Etienne
Saint-Etienne, France
Final polysomnography
Percentage of patients with AHI \< 15/hour through polysomnography assessment after nine months of follow-up in the training and the control groups
Time frame: 9 months
First intermediate polysomnography
Percentage of patients with AHI\<15/hour through polysomnography assessment after three months of follow-up in the training and the control groups.
Time frame: 3 months
Second intermediate polysomnography
Percentage of patients with AHI\<15/hour through polysomnography assessment after six months of follow-up in the training and the control groups.
Time frame: 6 months
High frequency
Correlation between change in AHI and change in high frequency (HF) of spectral analysis of heart rate variability (parasympathetic index) at 9 months of follow-up in the 2 groups
Time frame: 9 months
Maximal aerobic capacity (VO2Max)
Correlation between the change in VO2max during stress test, walking distance during 6 minutes and AHI in the two groups
Time frame: 9 months
Population Physical Activity questionnaire (POPAQ)
Correlation between the change in daily physical activity energy expenditure (estimated by the POPAQ questionnaire) and AHI in the two groups
Time frame: 9 months
Daily physical activity energy expenditure
Correlation between the daily physical activity energy expenditure (estimated directly by an actimetry sensor for 7 days) and AHI in the two groups
Time frame: 9 months
Epworth sleepiness Scale
Comparison of the variation of Epworth Sleepiness Scale (ESS) after 9 months follow-up for the two groups
Time frame: 9 months
Pittsburgh questionnaire
Comparison of the variation of Pittsburgh questionnaire after 9 months follow-up for the two groups
Time frame: 9 months
Berlin questionnaire
Comparison of the variation of Berlin questionnaire after 9 months follow-up for the two groups
Time frame: 9 months
Blood pressure - Baroreflex
Measure of autonomic function (parasympathetic activity) - quantified via changes in blood pressure
Time frame: 9 months
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