Trial to Evaluate the Immunogenicity and Safety of Panblok® (H7 rHA) in Healthy Adults Aged 18 and Older

Inclusion Criteria: 1. Adults, regardless of gender, aged 18 years and above 2. Able to give written informed consent to participate. 3. Body temperature \<100.0ºF. 4. The subject must be in reasonably good health as determined by targeted physical examination, when necessary, based on medical history. 5. Women of child-bearing potential (WOCBP) must have a negative urine pregnancy test within 24 hours preceding receipt of first and second vaccine doses. 6. Women are considered not of child-bearing potential if they are: * Surgically sterile * Menopausal, defined as no natural menses for ≥12 months 7. Comprehension of the study requirements, expressed availability for the required study period, and ability to attend scheduled visits and remote contacts. Exclusion Criteria: 1. Persons who previously received an H5N1 or H7N9 influenza vaccine or who plan to receive an H5N1or H7N9 influenza vaccine while participating in the study. 2. Persons who plan to receive a seasonal influenza vaccine earlier than Day 42 of participation in this study, i.e. before the post-vaccination serology sample is obtained. 3. Persons with an acute or chronic medical condition that, in the opinion of the investigator, would render vaccination unsafe or would interfere with the evaluation of immune responses. 4. Persons taking medications or treatments that may adversely affect the immune system, e.g. cytotoxic agents, immunosuppressive doses of corticosteroids, anti-TNFα agents. 5. Persons with an active neoplastic disease (excluding non-melanoma skin cancer that was successfully treated) or a history of any hematological malignancy. For this criterion, "active" is defined as having received treatment within the past 5 years. 6. Persons with a history of documented autoimmune disease. 7. Women currently pregnant, nursing mothers or women planning a pregnancy between enrollment and 42 days after randomization. 8. Persons who have had a prior serious reaction to any influenza vaccine. 9. Persons with a known history of Guillain-Barré Syndrome (GBS). 10. Persons with a history of anaphylactic-type reaction to injected vaccines. 11. Persons with a history of illicit drug use or alcohol abuse that may compromise the subject's ability to comply with the protocol. 12. Persons who received a seasonal influenza vaccine \< 6 months prior to enrollment (may delay enrollment). 13. Persons who received any licensed inactivated or recombinant (non-live) vaccine within 2 weeks prior to enrollment or any licensed live vaccine within 1 month prior to enrollment (may delay enrollment) (See separate exclusion criteria #1 and #12 for seasonal and H5N1 influenza vaccines.) 14. Persons who have had an acute illness or fever (\>38º C or \>100º F) within three days prior to study enrollment (enrollment may be delayed for full recovery, if acceptable to investigator). 15. Persons currently participating or planning to participate in a study that involves an experimental agent (vaccine, drug, biologic, device, or medication) or have received an experimental agent within 1 month prior to enrollment in this study, or who expect to receive another experimental agent during participation, or intend to donate blood during the 42-day primary study period. 16. Persons who received immunoglobulin or another blood product within the 3 months prior to enrollment in this study. Persons who expect to receive immunoglobulin or another blood product during the 42-day primary period of this study.