This study is aimed to assess the prevalence of thiamin deficiency in obese Thai children.
This study is a cross-sectional study. The objectives of the study are to determine the prevalence of thiamin deficiency in obese Thai children and to assess the associations of dietary factors and thiamin deficiency.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
SCREENING
Masking
NONE
Enrollment
124
If severe symptoms and signs of thiamine deficiency are present, thiamine is prescribed. Intervention 1 : severe symptom (heart failure, convulsion, or coma) : 50 mg thiamin administered very slowly intravenously, followed by a daily intramuscular dose of 10 mg for a week, and finally followed by 3-5 mg of thiamine per day orally for at least 6 weeks
no symptoms and signs of thiamine deficiency
If symptoms and signs of thiamine deficiency are present, thiamine is prescribed. If mild symptom : a daily oral dose of 10 mg thiamin during the first week, followed by 3-5 mg of thiamin per day orally for at least 6 weeks
Faculty of Medicine Siriraj Hospital
Bangkok, Thailand
abnormal thiamin pyrophosphate effect
Thiamin pyrophosphate effect will be measured by a blood test
Time frame: 7 days
consumption of thiaminase-containing foods and thiamin antagonist-containing foods
Food diary and food frequency questionaire will be required to evaluate food consumption
Time frame: 7 days
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