The investigators aimed to evaluate the efficacy of selective low volume ultrasound-guided blockades of the saphenous and obturator nerves on dynamic and rest pain 24-hours post-operatively for patients undergoing unilateral primary total knee arthroplasty.
A femoral nerve block is the recommended strategy in many surgical centers to supplement multimodal analgesic regime following total knee arthroplasty (TKA) (i.e. both for spinal and general anesthesia). However, a femoral nerve block will often result in quadriceps paralysis, and this will increase the risk for the patient to fall as long as the femoral block have effect. Thus, the search for sensory nerve blocks to stop pain after TKA is a very interesting topic. The saphenous nerve is a purely sensory nerve, and the posterior branch of the obturator nerve is a mixed nerve, where the motor component only affects part of the adductor major muscle.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
75
Ultrasound guided nerve blocks of the saphenous and obturator nerve, posterior branch with ropivacaine 0.75% for both nerve branches
nerve blocks of the saphenous nerve with ropivacaine 0.75% and obturator nerve, posterior branch with saline
Ultrasound guided nerve blocks of the saphenous and obturator nerve, posterior branch with saline for both nerve branches
Dynamic pain (pain upon movement) quantified as area-under-the-curve (AUC) 24-hours post-operatively
NRS 0-10
Time frame: 24 hours
Pain at rest quantified as area-under-the-curve (AUC) 24-hours post-operatively
NRS 0-10
Time frame: 24 hours
Total opioid consumption
mg
Time frame: 24 hours
Nausea and vomiting
NRS 0-10
Time frame: 24 hours
Time to first mobilization
hours
Time frame: 24 hours
Length of stay in recovery and hospital
hours
Time frame: 72 hours
Number of clinical complications
total number
Time frame: 72 hours
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