Use of Acellular Dermal in the Incarcerated Inguinal Hernia Tension-free Reconstructions

Xijing Hospital of Digestive Diseases100 enrolled

Overview

Incarcerated inguinal hernia is one of the common acute abdomen abdominal surgery, often prone to intestinal necrosis and acute peritonitis.Using traditional tension hernia reparation, the recurrence rate were as high as 30%. In recent years, biological materials especially acellular matrix materials (Acellular Dermal Matrix, ADM) in resisting the infection, has become a research hotspot. In the project, the investigators try to address the role of ADM in incarcerated inguinal hernia patients.

observation indicator: 1. recurrence rate after operation 2. incidence rate of complications 3. postoperative hospital stay 4. hospitalization costs 5. Self-evaluation of gastroesophageal reflux symptoms and quality of life(QOL) in 6th-month, 1st-year,2nd-year,3rd-year,4th-year and 5th-year after operation

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

100

Conditions

Incarcerated Inguinal Hernia

Interventions

ADM tension-free hernia reparationPROCEDURE

Use ADM as opposed to nothing to repair incarcerated inguinal hernia

Eligibility

Sex: ALLMin age: 16 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of incarcerated hernia * randomly select patch agreed by patients and family members Exclusion Criteria: * severe organ dysfunction * No-tolerate anesthesia * No-suitable for operation * glucocorticoid with long-term use * Sever intraperitoneal adhesion existed * spirit disease patients * automatically exit

Locations (1)

Xijing Hospital

Xi’an, Shanxi, China

Outcomes

Primary Outcomes

the recurrence rate after operation

Time frame: ten years

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.