Effectiveness and Safety of Autologous ADRC for Treatment of Anterior Cruciate Ligament Partial Rupture

Inclusion Criteria: * Patient suffers from partial rupture of anterior cruciate ligament (confirmed by MRI or knee arthroscopic surgery) * Clinically significant knee instability (positive anterior drawer test, pivot shift test, and Lachman test) * Patient is familiar with Participant information sheet * Patient signed informed consent form Non-inclusion Criteria: * Knee osteoarthritis grade III and grade IV * Medical history of autoimmune diseases * Patients prescribed for immunosuppressive treatment * Contraindications to the general or local anesthesia or medical history of allergic reactions to anesthetics * Subcompensated or decompensated forms of chronic diseases of internal organs * Significant weight loss (\> 10% of body weight in the previous year) of unknown etiology * Medical history of venous thromboembolism or estimated high risk of venous thromboembolism * Clinically significant abnormalities in results of laboratory tests * Any conditions limiting compliance (dementia, neuropsychiatric disease, drug and alcohol abuse etc.) * Participation in other clinical trials (or administration of investigational drugs) during 3 months prior inclusion * Patients with malignant tumors including postoperative period, patients receiving chemotherapy and/or radiotherapy. * Patient's activated partial thromboplastin time exceeds normal levels more than 1,8 times * Patients prescribed for anticoagulants treatment or patient received anticoagulants at least one hour prior lipoaspiration * Medical history of heterotopic ossifications * Patients prescribed for glycoprotein inhibitors treatment Exclusion Criteria: * Patient's refusal from the further participation in trial * Patient's refusal from compliance with the requirements of contraception during the participation in research * Chronic kidney disease IV - V stages (creatinine clearance \< 30 mL/min estimated by Cockroft-Gault formula) * Confirmed syphilis, HIV, hepatitis B or C infections Dropout Criteria: * Complete anterior cruciate ligament rupture confirmed by knee arthroscopic surgery * Pregnancy