The purpose of this study is to develop and test modified milk protein products to determine the effects of amino acids on food intake, satiety, insulin secretion and glucose control by insulin-independent action in healthy adults.
1. A total of 33 males and females will participate in the study. Capillary blood samples will be collected from all participants to measure plasma glucose over a 3.5 hour postprandial study. 2. Intravenous blood samples will be collected from a subset of 12 (6 males and 6 females) participants for determination of insulin, satiety hormones, acetaminophen (gastric emptying rates), and determination of amino acid profiles.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Enrollment
32
Milk treatments will be served with 58g of breakfast cereal.
University of Guelph- Human Nutraceutical Research Unit
Guelph, Ontario, Canada
Postprandial Glycemia, as measured by capillary blood glucose (mmol/L)
Time frame: 0-200 minutes
Postprandial Satiety, as measured by paper 100-mm visual analogue scale (mm)
Time frame: 0-200 minutes
Food Intake at ad libitum lunch meal, as measured by weighed pizza consumption (g)
Time frame: at 120 minutes
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