The purpose of this study is to assess the 2-year progression-free survival rate.
This was a prospective, open-label, multicenter, observational study. Participants who received bortezomib, Melphalan, Prednisone(VMP) therapy for Multiple myeloma (MM) that was not eligible for autologous stem cell transplantation will be enrolled in the study. The study will consist of Screening phase; VMP therapy phase (9cycles); Follow-up phase (2 years from the day when the first cycle was started). Participants visited each institution for evaluation for 2 years from the date of baseline evaluation and first VMP administration (duration of treatment, 9 cycles; follow-up visits, every 3 months after the end of the treatment). Participants receiving VMP therapy will be primarily evaluated for 2-year progression-free survival rate. Participants safety will be monitored throughout the study.
Study Type
OBSERVATIONAL
Enrollment
171
Participants receiving Bortezomib 1.3 milligram per square meter (mg/m2) will be observed in this study.
Participants receiving Melphalan 9 mg/m\^2 will be observed in this study.
Participants receiving Prednisone 60 mg/m\^2 will be observed in this study.
Unnamed facility
Anyang, South Korea
Unnamed facility
Busan, South Korea
Unnamed facility
Cheonan, South Korea
2-year Progression-free Survival Rate
Progression-free survival rate: the length of time from the day when Bortezomib was first administered to disease progression or death, whichever comes first, in 2 years.
Time frame: Up to 2 years
Time to Response
Time from the first day of Bortezomib administration to the day of confirmed first response in participants with confirmed response, or to the day of loss to follow-up, disease progression, death or completion of study therapy in participants without response.
Time frame: up to 2 years
Overall Response Rate
Percentage of participants who achieved CR, VGPR or PR in 2 years.
Time frame: up to 2 years
Complete Response Rate
Percentage of participants who achieved CR as best response.
Time frame: up to 2 years
Time to Next therapy
The next therapy after the end of the study therapy was investigated, and the time from the day when the first therapy was started to the day when the next therapy was started was calculated.
Time frame: up to 2 years
Time to Disease Progression
Time from the first day of Bortezomib administration to the day of disease progression or relapse from complete response, whichever comes first.
Time frame: up to 2 years
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Unnamed facility
Chungcheongbuk-Do, South Korea
Unnamed facility
Daegu, South Korea
Unnamed facility
Daejeon, South Korea
Unnamed facility
Gyeonggi-do, South Korea
Unnamed facility
Hwasun Gun, South Korea
Unnamed facility
Iksan, South Korea
Unnamed facility
Incheon, South Korea
...and 8 more locations