Pancreatic Enzyme Supplementation for Celiac Disease

Inclusion Criteria: * Biopsy proven celiac disease. * Age 18-80. * Ongoing symptoms defined as a CeD-GSRS score of greater than 3 during the run in period. * Subject must be following a gluten free diet. * tTG \< 40 units at screening. Exclusion Criteria: * Taking prescription or over the counter enzyme supplements for 1 month prior to enrollment. * Pregnant, breastfeeding or planning pregnancy. Woman using acceptable methods of contraception will be included. Acceptable methods of contraception include oral hormonal contraceptives, implanted hormonal contraceptives, diaphragm with spermicide, condoms, intra-uterine device, abstinence, and male partner vasectomy. * Patients with a pork allergy or who are unwilling to consume pork products. * English proficiency unsuitable for completion of surveys. * Known severe pancreatic disease. * Known history of prior cancer (except squamous or basal cell skin cancer). * Patients with lactose intolerance who are unable to tolerate a minimum of 1oz (2 tablespoons) of whole milk per day. * Clinically significant abnormality in safety lab values (i.e. CBC and BMP) at screening that may impact subject safety or the scientific integrity of the study. * Other known active GI condition including but not limited to inflammatory bowel disease, small intestine bacterial overgrowth, and obvious FODMAP intolerance. * History of all major gastrointestinal surgery other than appendectomy or cholecystectomy. * Comorbid condition that in the opinion of the investigator would interfere with the subject's participation in the study or would confound the results of the study.