Palliative Care Outcomes in the Management of Malignant Ascites by Interventional Radiology

Inclusion Criteria: * Refractory malignant ascites defined as ascites requiring more than one paracentesis to control patient symptoms despite medical therapy with diuretics and a. peritoneal fluid with cytology positive for malignant cells OR * Known malignancy with imaging findings of peritoneal carcinomatosis . * Eastern Cooperative Oncology Group (ECOG) performance score 3 * Age greater than or equal to 18 * Capable of giving informed consent Exclusion Criteria: * Life expectancy less than one month * Coagulopathy defined as international normalized ration (INR) \>2 which cannot be corrected with fresh frozen plasma * Platelet count \<50,000/microliter, which cannot be corrected with platelet transfusion * Active skin infections at sites where PVS would be inserted * Presence of infectious peritonitis or bacteremia * Neutropenia * American Heart Association Class D congestive heart failure (ie New York Heart Association Class IV) * Stage 5 CKD (ie GFR \< 15 mL/min) * Severe hypoalbuminemia defined as \< 2.2 g/dL * Loculated or hemorrhagic ascites * History of bleeding gastroesophageal varices * Inability to provide informed consent * Unable to participate in neuropsychological tests / questionnaires * Pregnant or nursing women * Anasarca