Effects of Mineralocorticoid Receptor Stimulation on Cognition

Charite University, Berlin, Germany80 enrolled

Overview

In this study the effects of mineralocorticoid stimulation on social cognition will be investigated in healthy young individuals.

80 healthy young individuals (40 females and 40 male) will be recruited an randomized to either placebo or 0.4 mg Fludrocortison before testing. Tasks will on emotion recognition, Task Switch, visual spacial memory and decision making will be conducted.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Enrollment

Conditions

Individuality

Interventions

FludrocortisoneOTHER

effects of fludrocortisone on cognition compared to placebo

Eligibility

Sex: ALLMin age: 18 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * free of medication * age 18 - 30 Exclusion Criteria: * any medication * severe illness

Locations (1)

Charite University

Berlin, Germany

Outcomes

Primary Outcomes

social cognition

computer based tests: emotion recognition

Time frame: 25 min

Secondary Outcomes

memory

computer based test on visuospacial memory

Time frame: 20 min

decision making

computer based tests: BART

Time frame: 25 min

Data from ClinicalTrials.gov

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