The Haemodynamic Effects of Mechanical Standard and Active Chest Compression-decompression During Out-of-hospital CPR

Physio-Control126 enrolled

Overview

The aim of this randomized out-of-hospital cardiopulmonary resuscitation study is to investigate haemodynamics generated by the standard mechanical external chest compression device (LUCAS™ 2) compared to a new version generating chest compressions and active decompression above the initial starting position of the suction cup (LUCAS™ 2AD).

Based on randomization patients will receive standard or active compression decompression chest compression and the haemodynamic effects will be compared.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

126

Conditions

Cardiac Arrest

Interventions

LUCAS2 ADDEVICE

LUCAS™ 2AD with compressions like the standard LUCAS™ 2 but added decompressions above the initial start position.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Unexpected adult out-of-hospital non-traumatic cardiac arrest where an attempt of resuscitation is considered appropriate in: * Patients 18 years or older Exclusion Criteria: * Traumatic cardiac arrest * Age believed to be less than 18 years * Known pregnancy * Victim not to be resuscitated (DNR orders) * Internals in prison * Included once in the study already * To Small/Large patients * Sustained ROSC occurring before the LUCAS™ 2 or LUCAS™ 2-AD can be applied to the patient, such that further CPR is not needed

Locations (1)

Oslo University hospital

Oslo, Norway

Outcomes

Primary Outcomes

Hemodynamics measured as EtCO2

Time frame: During 30 minutes of CPR

Secondary Outcomes

Intra arterial blood pressures,

Time frame: During 30 minutes of CPR

Oximetry,

Time frame: During 30 minutes of CPR

ROSC (Return of spontaneous circulation)

Time frame: During CPR

safety

Time frame: During 30 minutes of CPR

Data from ClinicalTrials.gov

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