Assessment of Bone Mineral Density During Pregnancy

Ain Shams University173 enrolled

Overview

BMD at peripheral sites typically heel is measured by Ultrasound densitometry at Ain Shams Maternity hospital.

Consecutive patients with singleton pregnancies between 36 and 39 weeks booked at a general obstetric clinic in a regional hospital will be recruited for the study. The obstetric department is a tertiary referral center in the region and part of a university teaching unit which catered to an annual delivery of around 10,000 women. A group of first trimester pregnant women with nearly the same age is recruited as controls.

Study Type

INTERVENTIONAL

Allocation

Purpose

SCREENING

Masking

NONE

Enrollment

173

Conditions

Bone Mineral Density Quantitative Trait Locus 3

Interventions

calcaneal quantitative ultrasound assessmentRADIATION

QUS for calcaneus bone of right foot will be done for this group of Pregnant women at the third trimester

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1\. females during 3rd trimister Exclusion Criteria: 1. Secondary causes of bone loss such as hyperparathyroidism. 2. Co-morbidities that would interfere with bone metabolism as clinically significant liver or renal disease. 3. Physical or orthopedic disabilities that would place the subject at risk or limit their ability to perform US. 4. Taking medication known to affect bone including steroid hormones. Histories of smoking and use of oral contraceptives (OCs) are not exclusion criteria.

Locations (1)

Faculty of medicine, ain shams university

Cairo, Cairo Governorate, Egypt

Outcomes

Primary Outcomes

Bone mineral density loss during pregnancy that is detectable by quantitative ultrasound at the os calcis.

Time frame: 6 months

Data from ClinicalTrials.gov

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