3D CT Guidance for Transjugular Intrahepatic Portosystemic Shunt Creation

West China Hospital15 enrolled

Overview

To prospectively evaluate the efficacy of real-time 3D CT-image guidance and CO2 portography during transjugular intrahepatic portosystemic shunt (TIPS) creation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Portal Hypertension

Interventions

CT-image guidanceDEVICE

TIPS creation is performed under the guidance of 3D CT-image.

CO2 portograms guidanceDRUG

TIPS creation is performed under the guidance of two-dimensional (2D) CO2 portograms.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Cirrhosis 2. Scheduled for indicated TIPS procedure Exclusion Criteria: 1. Presence of portal vein thrombosis 2. Presence of ascites 3. Presence of hepatic vein occlusion or stenosis 4. Proven malignancy including hepatocellular carcinoma 5. End-stage renal disease under renal replacement therapy; 6. Cardiorespiratory failure 7. Pregnancy or patients not giving informed consent for TIPS procedures

Outcomes

Primary Outcomes

Technical success rate

Time frame: procedure

Secondary Outcomes

Median needle passes for portal vein entry

Time frame: procedure

Median radiographic fluoroscopy time for portal vein entry

Time frame: procedure

The median radiation dose for the whole TIPS procedure

Time frame: procedure

The rate of TIPS complication

Time frame: 6 months

Data from ClinicalTrials.gov

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