A Single-center, Open Trials to Evaluate the Safety of Freeze-dried Group ACYW135 Meningococcal Conjugate Vaccine

Inclusion Criteria: * Healthy infants unimmunized Group A\&C meningococcal conjugate vaccine or Group A meningococcal polysaccharide vaccine which is above 2\~11 months-old, and healthy toddler more than 1-year-old without booster immunization. * The guardian or himself informed consent, and signed the informed consent form; * The guardian and family agreed to abide by the requirements of clinical trial scheme; * Participants has no history of immunoglobulin vaccination in the last 2 months / 2 months-old infants has no history of immunoglobulin vaccination after born, there is no history of other live vaccine inoculation before vaccination in 14 days, within 7 days without other inactivated vaccine immunization history; * the axillary temperature \< 37.1 ℃; * 2-months-old group in the age of 61-90 days; * 7-months-old group in the age of 211-300 days; * 1-year-old group in age of one full year of life. Exclusion Criteria: * Have allergies, convulsions, seizures, encephalopathy and psychiatric history or family history; * Neomycin, streptomycin and polymyxin B allergies; * With immunodeficiency, immunosuppressant therapy; * History of meningitis; * Women in lactation or pregnant; * Acute febrile diseases and infectious diseases; * History of labor abnormalities, choking rescue, congenital malformations, developmental disorders or serious chronic disease patients; * Had a severe allergic reaction of vaccination in the past; * Took oral steroids more than 14 days in last month; * Had high fever (axillary temperature≥38.0℃ or higher)in the past three days; * Prepare to attend or is in any other drug clinical study; * Meningococcal vaccine contraindications and any situation which researchers think that may affect test evaluation.