To Pace or Not to Pace in Sinus Node Disease

Abbott Medical Devices215 enrolled

Overview

Optimal pacing strategy for patients with SND is still unknown, although several publications in the past years demonstrated a deleterious effect of ventricular pacing. However, pacing has always been apical in these trials, and to which extent this absence of pacing is beneficial for patients with very long PR intervals is still to be found. The aim of this study is to compare ventricular septal pacing to no pacing in patients with SND.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

215

Conditions

Sinus Node Disease

Interventions

Septal ventricular pacingDEVICE

Ventricular pacing must be at least 90%, from the septum and with optimized AV delay

VIPDEVICE

Ventricular pacing must be less than 10%.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with sinus node disease Exclusion Criteria: * Complete or high degree AV block * Permanent atrial fibrillation

Locations (1)

CHU Pontchaillou - CCP

Rennes, France

Outcomes

Primary Outcomes

Left Ventricular Endsystolic Diameter (LVED)

Time frame: 18 months

Secondary Outcomes

AF incidence

Time frame: 18 months

Hospitalizations

Time frame: 18 months

Data from ClinicalTrials.gov

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